The at the very onset of the COVID-19 outbreak, initiated PCR testing for the SARS-CoV2 as it was of national importance to do so. Since identification of the first 91传媒n patient on the 10^th of March, they have currently carried out approximately 5000 PCR tests. Dedicated team of scientists have been working all seven days, late into the night, in order to provide such a service.

As an internationally reputed laboratory, carrying out cutting edge research on dengue pathogenesis and drug discovery, they are currently carrying out the following research activities in Collaboration with the National Institute of Infectious Disease, Colombo Municipality Council and University of Oxford.

1. Whole genomic sequencing of the SARS-CoV2 strains in 91传媒:
   They have established the technique of whole genomic sequencing in 91传媒 and so far, have completely sequenced 4 strains. They will continue this research of sequencing more virus strains to find out if certain strains contribute to virulence and if critical mutations occur in the viral strains in 91传媒
2. Antibody responses to SARS-CoV2: They have already initiated these experiments and their initial results have been shared with relevant authorities. They will also study the neutralizing antibody responses to SARS-CoV2, using a technique developed by Prof. Linfa Wang, of Duke NUS. Determining the neutralizing antibodies will also help them to identify potential donors for convalescent plasma treatment if needed in those with severe disease
3. Identifying biomarkers and inflammatory mediators that lead to severe disease: While most patients develop mild disease, some individuals develop pneumonia leading to fatalities. They are in the process of identifying inflammatory mediators and possible biomarkers that identify such people developing severe disease and also find out factors that cause severe disease.
4. Serosuvillence study in the community to determine the extent of silent infection: In collaboration with the CMC they are carrying out surveillance to determine the level of silent infection by antibody testing in the community.
5. T cell responses to the SARS-CoV2: They will be initiating T cell studies to determine cellular immune responses in mild vs severe disease to understand the factors leading to severe disease and prolong viral shedding.

Apart from the above, this team is collaborating with many other organizations in COVID-19 studies.

The post COVID-19 Testing and Research by USJ Centre for Dengue Research appeared first on USJ - 91传媒.

COVID-19聽喽秽窛喽溹逗 喽编窉喾冟窂 喽窉喽编窓喽编穵 喽窉喽� 喽洁窚喾�喽� 喽呧穭喾掄陡喾� 喾�喽� 喽⑧窊喾�喾掄董 喽多窔喽秽窂 喽溹窅喽编窊喽� 喾冟冻喾勦窂 喽戉侗喾娻侗喽稓喾� 喾勦窛 喾�喾權侗喽穵 喾冟窂喽秽穵喽稓 喽脆穵‍喽秽董喾掄稓喽秽穵喽膏逗喽氞穵 喾冟窚喽亨窂 喽溹侗喾娻侗喾� 喽窋喽秽窋 喽洁窚喾� 喽脆窋喽秽窂 喽⑧窊喾�喽穵喾�喽� 喽膏窉喽洁窉喽亨侗 喾冟秱喽涏穵‍喽亨董 喽脆窉喽秽窉喾冟稓喾� 喽窇喾冟穵 喽督喾娻穩喾� 喽多督喾� 喾冟窉喽о窉喽窉.

喽� 喾冟冻喾勦窂 喾冟窂喽秽穵喽稓 喽脆窉喾呧窉喽亨陡喽氞穵 喾冟窚喽亨窂 喽溹窅喽编窊喽膏锭 喾佮穵‍喽秽窊 喽洁秱喽氞窂喾�喾� 喾�喾掄动喾�‍喽亨窂喽ム逗喽编穵, 喽脆痘喾娻逗喾氞穫喽氞逗喽编穵 喾冟穭 喽编穩 喽编窉喽秽穵喽膏窂喽稓喽秽窋喾�喽编穵 喽� 喽编窚喽亨窓喽氞窋喽穵 喽呧董喾娻穭喽窂 喽多窅喽洁窊喽膏穵 喾冟窉喽窋 喽氞痘喽膏窉喽编穵 喾冟窉喽о窉喽窉.听 喽戉穭喾� 喾冟董喾斷锭喾斷动喾忇逗喽� 喽脆穵‍喽秽董喾掄兜喽洁逗喽氞穵 喾佮穵‍喽秽窊 喽⑧逗喾�喽秽穵喽班侗喽脆窋喽� 喾�喾掄穪喾娻穩喾�喾掄动喾�‍喽亨窂喽洁逗喾權侗喾� 喽呧穬喽编穵喽编锭 喽洁窅喽多窉喽窉.

COVID-19 喽秽窛喽溹逗喾�, A 喽氞窂喽穵喽┼逗喽� 喽呧逗喽穵 喾�喾涏痘喾冟逗 喾佮穵‍喽秽窊 喽洁秱喽氞窂喾�喾� 喽脆窅喽窉喽� 喽亨侗 喽多穩喽� 喽膏窔 喾�喽� 喾�喾掄锭 喾冟窉喽窋 喽氞穮 喽膏窎喽洁窉喽� 喽脆痘喾撪稓喾娻穫喽穩喽洁动喾� 喾勦冻喾斷侗喾� 喽溹窅喽编窊喽膏锭 喾勦窅喽氞窉喾�喾� 喽多穩 喾佮穵‍喽秽窊 喽⑧逗喾�喽秽穵喽班侗喽脆窋喽� 喾�喾掄穪喾娻穩喾�喾掄动喾�‍喽亨窂喽洁逗喾�, 喽┼窓喽傕稖喾� 喽脆痘喾娻逗喾氞穫喽� 喽膏栋喾�‍喽亨穬喾娻懂喾忇侗喽亨窔 喽呧栋喾�‍喽亨稓喾娻穫 喽膏穭喾忇稜喾忇痘喾娻逗 喽编窊喽洁窉喽氞窂 喽膏督喾�喾掄稖喾� 喾冟窔喾�喽亨锭 喽脆窅喾�喾冟窋喾�喾忇逗.

喾佮穵‍喽秽窊 喽洁秱喽氞窂喾�喾� 喽脆窅喽窉喽秽窓喽� 喾�喾涏痘喾冟逗 ‘A’ 喽氞窂喽穵喽┼逗喽� 喽呧逗喽穵 喾�喾�

COVID-19 喽洁窓喾� 喽编陡喾� 喽氞穮 喽秽窛喽溹逗 喽囙董喾� 喽氞痘喽� 喽编穩 喽氞窚喽秽窛喽编窂 喾�喾涏痘喾冟逗 SARS-CoV2 喽洁窓喾� 喾勦冻喾斷侗喾娻穩喽编窋 喽洁窅喽多窔.

喽戉陡 喾�喾涏痘喾冟逗喾� A,B 喾勦窂 C 喽洁窓喾� 喾勦冻喾斷侗喾娻穩喽� 喽膏窎喽洁窉喽� 喽嗋稓喾忇痘 喽窋喽编稓喾� 喾�喾掄动喾�‍喽亨窂喽ム逗喾掄侗喾� 喾勦冻喾斷侗喾忇稖喾權侗 喽窉喽多窔.

喽膏窔 喽脆痘喾娻逗喾氞穫喽逗 喽膏稖喾掄侗喾� 喽陡喽亨窉 喽夃董喾掄穭喾忇穬喽亨窔 喽脆穮喽膏窋 喾�喽窂喾�喽� 喽洁秱喽氞窂喾�喾氞动喾� 喾�喾涏痘喾冟逗喽� 喾冟陡喾娻洞喾栢痘喾娻东 喽⑧窂喽� 喾冟窅喽氞窅喾冟穵喽� 喾勦窚喽亨窂喽溹董喾娻董喾� – 喽膏穭喾忇稜喾忇痘喾娻逗 喽编窊喽洁窉喽氞窂 喽膏督喾�喾掄稖喾�

喽夃侗喾� 喽膏窔 喾�喽� 喾�喾掄锭 喾佮穵‍喽秽窊 喽洁秱喽氞窂喾�喾� 喾勦冻喾斷侗喾忇稖喽穵 喾�喾涏痘喾冟逗喾� A 喽氞窂喽穵喽┼逗喽� 喽呧逗喽穵 喽脆穵‍喽秽斗喾氞动喽� 喽囙陡喽秽窉喽氞窂喾� 喾冟穭 喽斷穬喾娻锭喾�‍喽秽窔喽洁窉喽亨窂喾�喾權侗喾� 喾�喾愢订喾� 喾�喾佮逗喾權侗喾� 喾�喾忇痘喾娻董喾� 喾�喽� 喽呧董喽� 喽犩窊喽编逗喾� 喾�喾斷穭喾忇侗喾� 喽脆穵‍喽秽动喾氞穪喽亨窓喽编穵 喾�喾愢订喾� 喾�喾佮逗喾權侗喾� 喾�喾忇痘喾娻董喾� 喾�喽编穵喽编窔 COVID-19 喽秽窛喽溹逗 喽囙董喾� 喽氞痘喽� 喾�喾涏痘喾冟逗喾� B 喽氞窂喽穵喽┼逗喾� 喽脆穵‍喽秽斗喾氞动喽� 喽多穩 喽� 喽膏穭喾忇稜喾忇痘喾娻逗 喽编窊喽洁窉喽氞窂 喽膏督喾�喾掄稖喾� 喽脆穵‍喽秽稓喾忇穪 喽氞穮喾忇逗.

喽编穩 喽氞窚喽秽窛喽编窂 喾�喾涏痘喾冟逗喾� C 喽氞窂喽穵喽┼逗 喾�喾愢订喾� 喾�喾佮逗喾權侗喾� 喽亨窋喽秽窛喽脆逗喾權侗喾� 喾�喾忇痘喾娻董喾� 喾�喾權陡喾掄侗喾� 喽窉喽多窔.

‘喽夃董喾掄穭喾忇穬喽溹董 喽脆痘喾撪稓喾娻穫喽逗喽氞穵’

喾佮穵‍喽秽窊 喽⑧逗喾�喽秽穵喽班侗喽脆窋喽� 喾�喾掄穪喾娻穩喾�喾掄动喾�‍喽亨窂喽洁逗喽� 喽呧逗喽穵 喽┼窓喽傕稖喾� 喽脆痘喾娻逗喾氞穫喽� 喽膏栋喾�‍喽亨穬喾娻懂喾忇侗喽� 喽窋喾� 喽脆窉喾勦窉喽о窉 喽秽穬喾忇逗喽编窂喽溹窂喽秽逗喾氞动喾� COVID-19 喽秽窛喽溹窊喽编穵 喾勦冻喾斷侗喾� 喽溹窅喽编窊喽膏锭 喽呧动喾忇穮 PCR 喽脆痘喾撪稓喾娻穫喽� 喽编窊喽洁窉喽氞窂 喽膏督喾�喾掄稖喾� 喽膏穭喾忇稜喾忇痘喾娻逗喾�喽秽窉喽亨稖喾� 喽脆穵‍喽秽栋喾忇侗喽穵喾�喽亨窓喽编穵 喽膏窔 喽窉喽编穩喽� 喾冟窉喽窋 喽氞痘喽编窋 喽洁窅喽多窔.

喽戉陡 喽脆痘喾撪稓喾娻穫喽� 喾冟冻喾勦窂 喽洁窅喽多窋喽窋 COVID-19 喽秽窛喽溹逗 喾�喾愢穮喽赤窋喽窋 喽呧逗喽溹窔 喽⑧窙喾� 喾冟窂喽膏穵喽脆督喾�喽洁窉喽编穵 喾�喾權侗喾娻稓喽� 喽溹董喾� 喾�喾涏痘喾冟逗喾� RNA (Ribo Nucleic Acid) 喽董喾娻董 喾冟窅喽氞窅喾冟穵喽� 喾�喾掄穪喾娻督喾氞穫喽逗 喽氞窉喽秽窊喽膏窔喽窊 喽膏窓喽� 喽董喾娻董喾娻穩喽� 喾勦冻喾斷侗喾忇稖喾愢侗喾撪陡喽� 喾勦窅喽氞窉 喾�喾� 喽窉喽多窔.

”喽膏窔 喽脆痘喾娻逗喾氞穫喽逗 喽膏稖喾掄侗喾� 喽陡喽亨窉 喽夃董喾掄穭喾忇穬喽亨窔 喽脆穮喽膏窋 喾�喽窂喾�喽� 喽洁秱喽氞窂喾�喾氞动喾� 喾�喾涏痘喾冟逗喽� whole genomic sequencing (喾�喾涏痘喾冟逗喾� 喽⑧窂喽� 喾冟窅喽氞窅喾冟穵喽�) 喾勦窚喽亨窂喽溹董喾娻董喾�. 喾佮穵‍喽秽窊 喽洁秱喽氞窂喾�喾氞动喾� 喾�喾涏痘喾� 喾�喽洁锭 喽呧动喾忇穮 喽脆痘喾撪稓喾娻穫喽� 喾冟窉喽窋 喽氞窉喽秽窊喽膏窔喽窊 喽膏窓喽窓喽氞穵 喽呧侗喾斷稖喽膏侗喽� 喽氞穮 喽氞穵‍喽秽陡喾�喾氞动喽� 喾�喾斷东喾� 喾�喾涏痘喾冟逗喾� 喽脆穵‍喽秽穩喾氞东喾掄稖喽� 喽洁稓喾娻穫喽� 喾冟穭喾掄董聽搁狈础听(Ribo Nucleic Acid)聽喾�喾權侗喾娻稓喽秽稖喾權侗 喾�喾愢订喾掄动喾斷痘 喽脆痘喾娻逗喾氞穫喽� 喾冟冻喾勦窂 喾�喾權侗喽穵 喽秽锭喽� 喽秽穬喾忇逗喽编窂喽溹窂喽秽逗喽氞锭 喽亨窅喾�喾撪陡喽亨窉. COVID-19 喾�喾涏痘喾冟逗喾� 喽脆穵‍喽秽斗喾氞动喽� 喽呧侗喾斷穩 喾冟秱喽氞窎喽洁董喾� 喾�喾權侗喾冟穵 喾�喽� 喽多穩喽� 喽膏董喽亨稓喾� 喽窉喽亨窓喽编穩喾�. 喽呧洞喾� 喽洁秱喽氞窂喾�喾� 喽脆窅喽窉喽秽窓喽� 喾�喾涏痘喾冟逗 喽编窉喾�喾愢痘喽窉喾� 喾勦冻喾斷侗喾忇稖喾愢侗喾撪陡 喽秽锭喽氞穵 喾�喾掄动喾掄逗喽� 喽膏窔 喾冟冻喾勦窂 喽膏窋喾勦窋喽� 喽窓喽编穵喽� 喽夃董喾� 喽� 喾�喾愢动喽溹董喾�,” 喽亨侗喾斷穩喾權侗喾� 喽膏穭喾忇稜喾忇痘喾娻逗喾�喽秽窉喽� 喾�喾掄穬喾娻董喽� 喽氞穮喾� 喽�.

喽膏窊喽� 喽呧动喾忇穮 喽脆痘喾撪稓喾娻穫喽� 喽穩喽窋喽秽锭喽穵 喾冟窉喽窋 喽氞痘喽� 喽多穩 喽� 喽囙逗 喽脆窅喾�喾冟窊喽�.

COVID-19 喽秽窛喽溹逗喾權侗喾� 喽脆窋喽穵喽溹督喽亨侗喾� 喽膏窉喽� 喽亨窂喽膏窔 喾冟窉喽穵喽班窉 喽囙陡喽秽窉喽氞窂喾� 喾勦窂 喽亨窋喽秽窛喽脆逗喾權侗喾� 喾�喾愢订喾� 喾�喾佮逗喾權侗喾� 喾�喾忇痘喾娻董喾� 喾�喾�. 喽窂喽亨窉喽洁侗喾娻董喽�, 喽膏窅喽洁窔喾冟窉喽亨窂喾�, 喾冟窉喽傕稖喽脆穵喽脆窋喽秽窋喾� 喾冟窅喽洁稓喾� 喾�喾掄锭 喽膏痘喽� 喾冟秱喽涏穵‍喽亨窂喾�喾� 喽呧订喾斷穩喽氞穵 喽稓喾娻侗喽� 喽洁窅喽多窓喽� 喽呧董喽� 喽戉陡 喽脆穵‍喽秽动喾氞穪喾�喽� 喽脆窅喽窉喽� 喽脆穩喽窉喽� 喾�喾涏痘喾冟逗喾� 喾冟穵喾�喽粪窂喾�喽� 喽娻锭 喾勦窔喽窋 喾�喾掄逗 喾勦窅喽氞窉 喽多穩喽� 喾�喾掄动喾�‍喽亨窂喽ム逗喾掄侗喾� 喽呧侗喾斷陡喾忇侗 喽氞痘喽亨窉.

“喽膏窔喽� 喽呧督喾斷董喾� 喾�喾涏痘喾冟逗喽氞穵 喽编窉喾冟窂 喾�喾掄稓喾樴董喾� 喾冟窉喽窋喾�喾氞稖喽� 喽亨侗喾�喾�. 喾冟窉喽傕稖喽脆穵喽脆窎喽秽窋喾�喾� 喽戉侗喾娻侗喽稓喾� 喾勦窅喽窋喾�喾溹董喾� 喽掄稓 喽洁秱喽氞窂喾�喽о董喾� 喾勦痘喾掄逗喽编穩 喽� 喽氞窉喽亨督 喽多督喽编穵喽� 喽洁秱喽氞窂喾�喾� 喾�喾涏痘喾� 喽氞窂喽穵喽┼穩喽� 喽窉喽亨窓喽� 喾�喾權侗喾冟穵喽氞陡喾�, 喽呧侗喾掄董喾� 喽秽锭喾�喽� 喽窉喽亨窓喽� 喾�喾權侗喾冟穵喽氞陡喾� 喽多督喽编穵喽� 喽曕侗喾�. 喽掄稓喽� 喽呧洞喾� 喽洁秱喽氞窂喾�喾� 喽膏窔 喾�喾涏痘喾冟逗喾� whole genomic sequencing 喽氞窉喽亨侗 喽戉稓 喾冟窚喽亨窂 喽溹窅喽编窊喽� 喽夃董喾� 喾�喾愢动喽溹董喾�,” 喽亨侗喾斷穩喾權侗喾� 喽膏穭喾忇稜喾忇痘喾娻逗 喽编窊喽洁窉喽氞窂 喽膏督喾�喾掄稖喾� 喽氞窉喽亨窂 喾冟窉喽о窉喽亨窂 喽�.

The post 喽⑧洞喾斷痘 喽脆痘喾娻逗喾氞穫喽氞逗喾掄侗喾娻稖喾權侗喾� 喽夃董喾掄穭喾忇穬喽溹董 喾冟窚喽亨窂喽溹窅喽编窊喽膏稓喾� – 喾佮穵‍喽秽窊 喽洁秱喽氞窂喾�喾� COVID 19 喾�喾涏痘喾� 喽囙陡喽秽窉喽氞窂喾�喾� 喾冟穭 喽曕穬喾娻锭喾�‍喽秽窔喽洁窉喽亨窂喾�喾� 喽氞窂喽穵喽� 喾�喽洁锭 喾冟陡喾忇侗喽亨窉 appeared first on USJ - 91传媒.

The 91传媒 is one of the leading laboratories in 91传媒, which is carrying out diagnostics for COVID-19.

Currently several strains of the SARS-CoV2 virus are circulating in the world and some strains are thought to be more virulent than others.

As infected patients came to 91传媒 from all over the world, the team of scientists at the Centre for Dengue Research at the Allergy, Immunology and Cell Biology Unit have sequenced the viruses in 91传媒.

This is the first time whole genomic sequencing of viruses has been carried out in 91传媒. In all previous instances, when virus sequencing was required, samples have been sent overseas for this purpose. Therefore, the scientists at USJ have taken a gigantic step forward, by initiating whole genomic sequencing in 91传媒 and providing invaluable data regarding the virus strains here.

The research team was led by Prof Neelika Malavige with the participation of Dr. Chandima Jeewandara and other research scientists attached to the Faculty of Medical Sciences at 91传媒.

According to the data four 聽SARS-CoV2 virus strains are circulating among 91传媒n Covid-19 infected patients.

The post USJ Dengue Research Scientists Sequenced SARS-CoV2 (Coivd19) Viruses First Time in 91传媒 appeared first on USJ - 91传媒.

The IRCHSS 聽was held at the 91传媒 on 3rd December 2015. It was organized by the Faculty of Humanities and Social Sciences and featured both local and international researchers. This year’s theme was “Today’s Vision, Tomorrow’s Reality: Success through Synergy”. The inauguration ceremony took place with the Chancellor of the university, Ven.Bellanwila Wimalarathana Thero as chief guest and Prof.Vinnie Vitharana as guest of honour. Taking the contemporary social issues on reconciliation into consideration, Ven.Bellanwila Wimalarathana Thero in his address, stated that reconciliation should be for people in all walks of life and academics play a major role in taking them among the public.

Among other distinguished guests were, Vice Chancellor Prof.Sampath Amaratunge, Emeritus Prof.Wimal G.Balagalle, Prof.Rowland S.Laura of the University of Newcastle – Australia,Ven.Khammai Dhammasami, Mr.Lasantha Nawaratne – Dean , Faculty of Humanities and Social Sciences, Dr.Chamalie Nahallage – Conference Chair and Ven.Dr.M.Vijithadhamma – Conference Secretary. A large number of local and foreign members of Buddhist clergy attended the conference, which was a significant addition to the IRCHSS. The keynote speech was delivered by Prof.Rowland S.Laura who brought forth interesting facts on human communication and quality of life in an age where machines have started to dominate the society.

Two guest speakers, Prof.Rajiva Wijesinghe and Prof.T.Thanaraj, also participated at the symposium on reconciliation. A considerable number of research papers were discussed at the Technical sessions during the afternoon, where academics shared knowledge on a variety of subjects relating to the fields of聽humanities and social sciences.

The conference lasted the entire day 聽and was concluded with the award ceremony and a cultural show.

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In recent past, the dengue threat had been spreading among the university community in a considerable manner. The university officials have held several discussions with health and other relative officials to bring solutions to the matter. The shramadana adds to this continuous effort. Probable mosquito breeding places were identified and duly cleaned up, making the university grounds a health-wise secure area.

The post Shramadana by staff and students to prevent dengue spread appeared first on USJ - 91传媒.

But for this major issue, there is neither a proper vaccine to prevent infections nor effective antiviral drug. The prevention is only sought by reducing the habitat and the number of mosquitoes and limiting exposure to bites. In order to develop a safe and effective vaccine, researchers all around the globe try to expand the knowledge about dengue at the moment.

Although the number of infections is high, only around 10% develop apparent and severe forms of dengue infection which is called dengue hemorrhagic fever or shock syndrome. And 90% of the infected individuals show only a mild illness or do not show any clinical symptoms at all. The severe forms of dengue occur with increased leaking of fluid from the capillaries.

Dr. Neelika Malavige, Senior Lecturer in Department of Microbiology, Faculty of Medical Sciences; focuses on investigating the mediators that cause vascular leak in dengue. Dr. Malavige has identified a potential mediator and a clinical trial for a drug for the treatment is on progress.

Another aim of studies of Dr. Malavige is to find out why 90% of the infected individuals do not show severe dengue and what causes the virus to develop asymptomatic decease or protective immune response. Currently a large scale research project is being done, involving over 1500 individuals to find out the protective immune response to dengue. This study is mainly concentrated on T cell responses and antibody responses in dengue viral infection.

Selected Research Papers by聽Dr. Neelika Malavige

Pathogenesis of liver involvement during dengue viral infections

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Apart from work on Dengue pathogenesis and immune responses, the researchers have also developed a mobile application for real time tracking of Dengue epidemics. A pilot study in the Dehiwala MOH Division to digitalise all addresses of Dengue patients from 2010 to 2014 October, in order to determine geo-spatial factors responsible for Dengue transmission, has just been completed. The Mobile Technology Application developed by the CDR-GIS Team is soon to be launched. The Google Asia Conference of Web Application Developers, held in 91传媒 in September 2014, has identified the work of CDR as most innovative and selected the proposal on Mobile Application Development for Dengue Control. Apart from the above activities, research work of the team has been published in 3 high impact factor international journals, and presented at 6 conferences, winning one international and two local awards for the year 2014.

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